Jing He , Li Jun

Animal Science Research Center, Cuixi Academy of Biotechnology, Zhuji, 311800, Zhejiang, China
Author    Correspondence author
International Journal of Molecular Evolution and Biodiversity, 2024, Vol. 14, No. 6   
Received: 05 Oct., 2024    Accepted: 16 Nov., 2024    Published: 04 Dec., 2024

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

This study summarizes the research progress on phylogeny and molecular evolution of domestic goats (Capra aegagrus hircus). It mainly introduces the genetic differences between domestic goats and their wild ancestors, such as bezoar goats. The study also talks about the genetic diversity between different groups of domestic goats. We analyzed mitochondrial DNA and whole genome data. These data help us understand how goats adapt to different environments and reveal what natural selection and genetic changes they have experienced during evolution. The article also mentions some commonly used genetic research methods, such as genome-wide association analysis (GWAS) and CRISPR/Cas9 technology. These tools have enabled us to discover many important genetic changes that have occurred during domestication, such as the increase in genes controlling certain traits and the changes in some special genetic markers. This review can provide some theoretical references and practical suggestions for goat breeding, genetic improvement and protection of germplasm resources.

Phylogeny; Molecular evolution; Goat genomics; Genetic diversity; Gene editing